Born in Penang in the British Straits Settlements, Wu won a scholarship to Cambridge and pursued further study in Europe. He returned to Malaya before moving to China in 1908, carrying bacteriological credentials across imperial and national boundaries.
After the plague emergency, he helped establish hospitals, medical education, the Chinese Medical Association, and a national quarantine service. He also campaigned against opium and represented China in international health forums.
Public-health modernisation was not culturally neutral. New institutions could strengthen national sovereignty and save lives while also extending surveillance and professional authority over local practices.