Finlay practised in Havana and studied yellow fever in a region repeatedly struck by epidemics. He presented “The Mosquito Hypothetically Considered as the Transmitting Agent of Yellow Fever” to Havana's scientific academy in August 1881. Many colleagues remained unconvinced.
In 1900 the United States Army Yellow Fever Board, led by Walter Reed, worked in Cuba and used mosquitoes and methods connected to Finlay's research. Its controlled experiments supplied stronger evidence for mosquito transmission while exposing volunteers to grave risk. The board's institutional prestige often overshadowed the Cuban origin of the hypothesis.
Vector control led by William Gorgas and others sharply reduced yellow fever in Havana, and similar methods later served the United States canal project in Panama. Public-health success was therefore entangled with military occupation, labour control, commerce, and imperial infrastructure.
- 1833: Finlay is born in Puerto Príncipe, Cuba.
- 1881: he presents the mosquito transmission hypothesis in Havana.
- 1900: the Reed board produces widely accepted experimental evidence in Cuba.
- 1902: Finlay joins the organising committee of the International Sanitary Bureau, later PAHO.
- 1902-1909: he serves as Cuba's chief sanitary officer.