Drew studied at Amherst and McGill before surgical training in Montreal and New York. At Columbia he completed doctoral research on banked blood, combining laboratory investigation with the practical demands of transfusion.
He returned to Howard University and became head of surgery at Freedmen's Hospital. Major white institutions restricted Black trainees, so Howard carried an outsized responsibility for producing surgeons who would serve Black communities and challenge professional exclusion.
Drew treated teaching, operative discipline, research, and professional comportment as connected. His students extended his influence far beyond the wartime projects for which he became famous.